Vignettes

Developed for practical use: below you find a collection of practical examples and use-cases, the so-called rpact vignettes.

In addition to these public open access vignettes, our RPACT SLA customers have access to exclusive vignettes on special topics such as the analysis of multi-stage data with covariates from raw data.

# Title Category Sort descending Endpoint Summary
3 Designing Group Sequential Trials with a Binary Endpoint with rpact Planning Categorical

This R Markdown document provides examples for designing trials with binary endpoints using rpact.

14 Planning a Trial with Binary Endpoints with rpact Planning Categorical

This R Markdown document provides an example for planning a trial with a binary endpoint using rpact. It also illustrates the use of ggplot2 for illustrating the characteristics of a sample size recalculation strategy. Another example for planning a trial with binary endpoints can be found in the vignette Designing group sequential trials with a binary endpoint with rpact.

Sample size, Power simulation
4 Designing Group Sequential Trials with Two Groups and a Survival Endpoint with rpact Planning Survival

This R Markdown document provides examples for designing trials with survival endpoints using rpact.

1 Defining Group Sequential Boundaries with rpact Planning Categorical, Continuous, Survival

This R Markdown document provides example code for the the definition of the most commonly used group-sequential boundaries in rpact.

15 Planning a Survival Trial with rpact Planning Survival

This R Markdown document provides an example for planning a trial with a survival endpoint using rpact thereby illustrating the different ways of entering recruitment schemes. It also demonstrates the use of the survival simulation function.

Power simulation, Sample size
13 Using the Inverse Normal Combination Test for Analysing a Trial with Continuous Endpoint and Potential Sample Size Re-Assessment with rpact Analysis Continuous

This R Markdown document provides an example for analysing trials with a continuous endpoint and sample size reassessment using rpact.

21 Analysis of a Multi-Arm Design with a Binary Endpoint using rpact Analysis Categorical

This R Markdown document shows how to analyse and interpret multi-arm designs for testing proportions with rpact.

Multi-arm
7 Analysis of a Group Sequential Trial with a Survival Endpoint using rpact Analysis Survival

This R Markdown document provides examples how to analyse a survival trial and provide inference throughout and at the end of the trial with rpact.

9 How to use R Generics with rpact Utilities Categorical, Continuous, Survival

This R Markdown document provides many different examples that illustrate the usage of so-called R generic functions (short: R generics) with rpact, e.g., as.data.frame or summary.

18 How to Create One- and Multi-Arm Analysis Result Plots with rpact Utilities Categorical, Continuous, Survival

This R Markdown document provides many different examples for creating one- and multi-arm analysis result plots with rpact and ggplot2.

Analysis

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