Developed for practical use: below you find a collection of practical examples and use-cases, the so-called rpact vignettes.
In addition to these public open access vignettes, our RPACT SLA customers have access to exclusive vignettes on special topics such as the analysis of multi-stage data with covariates from raw data.
# | Title | Category Sort descending | Endpoint | Summary |
---|---|---|---|---|
6 | An Example to Illustrate Boundary Re-Calculations during the Trial with rpact | Planning | Survival | This R Markdown document provides an example for updating the group sequential boundaries when using an alpha-spending function approach based on observed information rates in rpact. Since version 3.1 of rpact, an additional option in the |
5 | Simulation-Based Design of Group Sequential Trials with a Survival Endpoint with rpact | Planning | Survival | This R Markdown document describes how to simulate design characterics for survival design under complex settings (incl. non-proportional hazards) in rpact. Power simulation |
11 | Comparing Sample Size and Power Calculation Results for a Group Sequential Trial with a Survival Endpoint: rpact vs. gsDesign | Planning | Survival | This R Markdown document provides an example that illustrates how to compare sample size and power calculation results of the two different R packages rpact and gsDesign. |
2 | Designing Group Sequential Trials with Two Groups and a Continuous Endpoint with rpact | Planning | Continuous | This R Markdown document provides examples for designing trials with continuous endpoints using rpact. |
26 | Delayed Response Designs with rpact | Planning | Categorical, Continuous, Survival | This R Markdown document provides a brief introduction to group sequential designs with delayed responses as proposed by Hampson and Jennison (2013). It is shown how this is implemented in rpact. Examples for designing trials with delayed responses using the software are provided. We also describe an alternative approach that directly uses the α-spending approach to derive the decision boundaries. |
21 | Analysis of a Multi-Arm Design with a Binary Endpoint using rpact | Analysis | Categorical | This R Markdown document shows how to analyse and interpret multi-arm designs for testing proportions with rpact. Multi-arm |
7 | Analysis of a Group Sequential Trial with a Survival Endpoint using rpact | Analysis | Survival | This R Markdown document provides examples how to analyse a survival trial and provide inference throughout and at the end of the trial with rpact. |
13 | Using the Inverse Normal Combination Test for Analysing a Trial with Continuous Endpoint and Potential Sample Size Re-Assessment with rpact | Analysis | Continuous | This R Markdown document provides an example for analysing trials with a continuous endpoint and sample size reassessment using rpact. |
18 | How to Create One- and Multi-Arm Analysis Result Plots with rpact | Utilities | Categorical, Continuous, Survival | This R Markdown document provides many different examples for creating one- and multi-arm analysis result plots with rpact and ggplot2. Analysis |
10 | How to Create Admirable Plots with rpact | Utilities | Categorical, Continuous, Survival | This R Markdown document provides many different examples for creating plots with rpact and ggplot2, e.g. the |
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