Developed for practical use: below you find a collection of practical examples and use-cases, the so-called rpact vignettes.
In addition to these public open access vignettes, our RPACT SLA customers have access to exclusive vignettes on special topics such as the analysis of multi-stage data with covariates from raw data.
# | Title | Category Sort descending | Endpoint | Summary |
---|---|---|---|---|
11 | Comparing Sample Size and Power Calculation Results for a Group Sequential Trial with a Survival Endpoint: rpact vs. gsDesign | Planning | Survival | This R Markdown document provides an example that illustrates how to compare sample size and power calculation results of the two different R packages rpact and gsDesign. |
2 | Designing Group Sequential Trials with Two Groups and a Continuous Endpoint with rpact | Planning | Continuous | This R Markdown document provides examples for designing trials with continuous endpoints using rpact. |
26 | Delayed Response Designs with rpact | Planning | Categorical, Continuous, Survival | This R Markdown document provides a brief introduction to group sequential designs with delayed responses as proposed by Hampson and Jennison (2013). It is shown how this is implemented in rpact. Examples for designing trials with delayed responses using the software are provided. We also describe an alternative approach that directly uses the α-spending approach to derive the decision boundaries. |
12 | Supplementing and Enhancing rpact’s Graphical Capabilities with ggplot2 | Planning | Continuous | The aim of this R Markdown document is to give a brief description on how easy it is to supplement and enhance plots generated in rpact by use of the ggplot2 package and associated language. Power simulation |
20 | Simulating Multi-Arm Designs with a Continuous Endpoint using rpact | Planning | Continuous | This R Markdown document provides examples for simulating multi-arm multi-stage (MAMS) designs for testing means with rpact. Power simulation, Multi-arm |
7 | Analysis of a Group Sequential Trial with a Survival Endpoint using rpact | Analysis | Survival | This R Markdown document provides examples how to analyse a survival trial and provide inference throughout and at the end of the trial with rpact. |
13 | Using the Inverse Normal Combination Test for Analysing a Trial with Continuous Endpoint and Potential Sample Size Re-Assessment with rpact | Analysis | Continuous | This R Markdown document provides an example for analysing trials with a continuous endpoint and sample size reassessment using rpact. |
21 | Analysis of a Multi-Arm Design with a Binary Endpoint using rpact | Analysis | Categorical | This R Markdown document shows how to analyse and interpret multi-arm designs for testing proportions with rpact. Multi-arm |
8 | Defining Accrual Time and Accrual Intensity with rpact | Utilities | Survival | This R Markdown document provides a technical view on the different alternatives to define accrual time and accrual intensity with rpact. |
17 | How to Create Summaries with rpact | Utilities | Categorical, Continuous, Survival | This R Markdown document provides many different examples that illustrate the usage of the R generic function |
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